We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
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Most Useful Reviews
9
Increased energy
3 people found this helpful
I feel it working! After giving birth, I struggled with fatigue, but since taking this supplement, my energy levels have significantly improved. There’s a big difference on days I take it compared to when I don’t. I will definitely buy it again.
Read More
9
Fatigue management
1 people found this helpful
After feeling tired every day post-work, I bought these vitamins based on recommendations. They have worked remarkably well for my fatigue and even helped with my bears.
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9
Fatigue melting away
1 people found this helpful
It works! This vitamin B-100 helps me recover from fatigue without needing garlic injections. I feel lighter, and it has greatly assisted my partner and me, as we approach menopause. I also take vitamins C and E alongside.
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 29 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
9
Increased energy
3 people found this helpful
I feel it working! After giving birth, I struggled with fatigue, but since taking this supplement, my energy levels have significantly improved. There’s a big difference on days I take it compared to when I don’t. I will definitely buy it again.
Read More
9
Fatigue management
1 people found this helpful
After feeling tired every day post-work, I bought these vitamins based on recommendations. They have worked remarkably well for my fatigue and even helped with my bears.
Read More
9
Fatigue melting away
1 people found this helpful
It works! This vitamin B-100 helps me recover from fatigue without needing garlic injections. I feel lighter, and it has greatly assisted my partner and me, as we approach menopause. I also take vitamins C and E alongside.
Read More
9
Increased energy
1 people found this helpful
Excellent! I recommend it! Before taking these vitamins for chronic fatigue syndrome, I felt persistently fatigued with no motivation. After about three weeks, I've become more energetic and feel much better.
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7.5
Health improvements
1 people found this helpful
I faced chronic fatigue syndrome and struggled with everyday tasks. I've learned that B vitamins are essential for energy cycles. Although I notice a B vitamin smell when I burp, it doesn't bother me. I'm trying other B vitamins and see improvements in my health.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
While there is no definitive cure for Chronic Fatigue Syndrome (CFS), some research suggests that Vitamin B Complex may play a supportive role in managing symptoms. The B vitamins, including B1, B2, B3, B5, B6, B7, B9, and B12, are essential for energy production and metabolic processes in the body. Many individuals with CFS report low energy levels and fatigue, which can be exacerbated by deficiencies in these vitamins. Supplementing with a B Complex may help improve energy levels, cognitive function, and overall well-being for some, although results can vary from person to person.
It's important to note that while B vitamins may be beneficial, they should not be viewed as a substitute for a comprehensive treatment plan. Consulting with a healthcare professional is crucial for personalized advice and proper diagnosis. Should you decide to try a Vitamin B Complex, look for high-quality products that include the full range of B vitamins and consider discussing with your doctor for tailored recommendations that complement any existing treatment strategies.
Based on user reviews, the timeline for experiencing results from this supplement for Chronic Fatigue Syndrome can vary, but many users suggest noticeable improvements within a few weeks of consistent use. One reviewer reported feeling more energetic and significantly better after approximately three weeks of taking the vitamins Read Review. Similarly, another user mentioned a marked reduction in fatigue soon after they started taking the supplement Read Review.
However, it's worth noting that some individuals may take longer to experience the full benefits, as personal responses to supplements can differ. For instance, a user highlighted that consistent use led to a significant improvement in their overall energy levels, reinforcing the idea that regular consumption is key Read Review. Overall, it's advisable to give the supplement a few weeks to see how your body responds, while keeping in mind that ongoing usage often yields the best results.
Vitamin B12 and folic acid may offer some benefits for individuals with Chronic Fatigue Syndrome (CFS), as suggested by a study involving 38 patients with myalgic encephalomyelitis (ME), a condition often associated with CFS. The research indicated that those receiving vitamin B12 injections alongside folic acid exhibited varying responses; some patients—termed "Good" responders—experienced significant improvements, particularly when given more frequent injections and higher doses. In contrast, "Mild" responders showed limited benefits, indicating the complexity and individualized nature of treatment for CFS. This variability suggests that while these supplements hold potential, their effectiveness can differ significantly from person to person [1].
Despite these findings, it’s crucial to note that the study calls for further research to establish the most effective treatment regimens. This underscores the necessity of personalized approaches to managing chronic fatigue symptoms, given the mixed results in treatment responses. While vitamin B12 and folic acid might be a part of the conversation regarding CFS management, they should be viewed as part of a broader strategy that requires careful consideration and ongoing research to optimize therapeutic outcomes for patients [1].
Users have reported a range of positive improvements in their symptoms of fatigue after taking this supplement. Many individuals have experienced significant boosts in energy levels, with one user noting that there was a "big difference" in her energy on days she took the supplement compared to when she didn't Read Review. Another user mentioned feeling "much better" and more energetic after approximately three weeks of consistent usage, which aligns with various reviews highlighting that B vitamins are essential for energy cycles and have noticeably reduced fatigue symptoms Read ReviewRead Review.
Several reviewers found enhanced recovery from chronic fatigue by taking the supplement regularly. For example, one individual shared that it "helped speed up recovery" especially during strenuous activities Read Review. Others have noted planned repurchases due to improved energy and less physical exhaustion Read Review. Nevertheless, it's important to acknowledge that individual results can vary significantly, and while many users report beneficial effects, others may not experience the same level of improvement. Factors such as diet, lifestyle, and personal health conditions can all play a role in the effectiveness of the supplement.
Many users report positive experiences when combining this supplement with other vitamins to manage Chronic Fatigue Syndrome. One reviewer noted that taking B-100 alongside vitamins C and E has significantly helped in recovery from fatigue, highlighting that it worked well for both her and her partner approaching menopause Read Review. Other users have similarly mentioned incorporating additional supplements into their regimen; for instance, one person stated that they effectively manage fatigue alongside other vitamins Read Review.
Additionally, users appreciate the sustained-release formulation of the supplement, which allows for a gradual release of energy throughout the day. One reviewer shares that on particularly demanding days, they even supplement their intake with an additional tablet to enhance their energy levels further Read Review. However, it's crucial to approach this with caution and monitor one's own response, as effects can vary greatly among individuals depending on personal health conditions or dietary habits. Overall, many users are enthusiastic about the beneficial effects of this supplement, especially when taken in combination with other vitamins to combat fatigue Read Review.
According to the research conducted on the effects of vitamin B12 and folic acid for Chronic Fatigue Syndrome (CFS), the responses to treatment can vary significantly among individuals. The study involved 38 patients with myalgic encephalomyelitis (ME), where it was observed that those classified as "Good" responders experienced greater improvements when receiving more frequent injections and higher doses of both vitamin B12 and folic acid [1]. This suggests that patients may benefit from customized treatment plans that include higher doses of these supplements, especially for those who show promising initial responses.
However, it is important to note that the study also found that "Mild" responders showed limited improvement, indicating the need for further research to better understand the optimal dosages and combinations that might work for different individuals. Therefore, while higher doses might be more beneficial for some, the variability in response underscores the necessity for tailored approaches in treating CFS with Vitamin B Complex [1]. As always, consulting with a healthcare provider before making any changes to supplementation is crucial.
9
Increased energy
1 people found this helpful
Excellent! I recommend it! Before taking these vitamins for chronic fatigue syndrome, I felt persistently fatigued with no motivation. After about three weeks, I've become more energetic and feel much better.
7.5
Fatigue relief
I initially purchased these to tackle chronic fatigue syndrome and assist with weight loss, and I've definitely noticed a reduction in my fatigue levels.
9
Combatting fatigue
This product is perfect for fighting chronic fatigue syndrome! I have noticed a significant improvement in my overall energy levels.
9
Increased energy
3 people found this helpful
I feel it working! After giving birth, I struggled with fatigue, but since taking this supplement, my energy levels have significantly improved. There’s a big difference on days I take it compared to when I don’t. I will definitely buy it again.
7.5
Health improvements
1 people found this helpful
I faced chronic fatigue syndrome and struggled with everyday tasks. I've learned that B vitamins are essential for energy cycles. Although I notice a B vitamin smell when I burp, it doesn't bother me. I'm trying other B vitamins and see improvements in my health.
7.5
Fatigue relief
15 people found this helpful
I’m grateful for the continuous release of B vitamins that help maintain my energy levels for longer. I take B-100 before days of heavy exercise and find it has helped speed up recovery from chronic fatigue syndrome. While it does smell stronger than capsules, storing it in the fridge reduces the odour slightly. I notice my urine turns yellow, a common effect. I avoid taking it before bed as it can disrupt my sleep.
7.5
Energy boost
4 people found this helpful
This supplement improved my energy and reduced my physical fatigue after I began taking it. The large tablets have a peculiar smell, but it doesn’t bother me. I plan to repurchase it.
9
Fatigue melting away
1 people found this helpful
It works! This vitamin B-100 helps me recover from fatigue without needing garlic injections. I feel lighter, and it has greatly assisted my partner and me, as we approach menopause. I also take vitamins C and E alongside.
7.5
Healthy nails
2 people found this helpful
After taking this supplement regularly, I’ve noticed my nails have become thicker and grow faster. It's effective alongside other supplements for skin quality and fatigue management. I always keep a stock on hand as the results are impressive.
7.5
Fatigue alleviation
1 people found this helpful
This sustained-release type allows for one tablet daily, which helps combat chronic fatigue syndrome. On particularly exhausting days, I add another tablet in the evening for extra support. This way, I manage my intake and feel great.
7.5
Reduced fatigue
1 people found this helpful
I've consistently taken these mega vitamins, and they've greatly reduced my physical and mental fatigue. While I experienced a skin reaction initially, cutting back resolved it, and I found that the vitamin B mix is effective, helping to combat my chronic fatigue syndrome. The tablets are quite large, and they make my urine turn yellow.
7
B12 and folic acid show variability
Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
References
Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648